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Natural Fat Loss Steroids CAS 84485-00-7 Oral Anorexiant for Men Muscle Growth
Sibutramine (usually in the form of the hydrochloride monohydrate salt) is an oral anorexiant. Until 2010 it was marketed and prescribed as an adjunct in the treatment of exogenous obesity along with diet and exercise.
CAS No: 84485-00-7
Appearance: White powder, soluble in methanol.
Medicine reducing weight and antidepressants.
Sibutramine is well absorbed from the GI tract (77%), but undergoes considerable first-pass metabolism, reducing its bioavailability. The drug itself reaches its peak plasma level after 1 hour and has also a half-life of 1 hour. Sibutramine is metabolized by cytochrome P450 isozyme CYP3A4 into two pharmacologically-active primary and secondary amines (called active metabolites 1 and 2) with half-lives of 14 and 16 hours, respectively. Peak plasma concentrations of active metabolites 1 and 2 are reached after three to four hours. The following metabolic pathway mainly results in two inactive conjugated and hydroxylated metabolites (called metabolites 5 and 6). Metabolites 5 and 6 are mainly excreted in the urine.
|Description||White to kind of white powder||kind of white powder|
|Solubility||Soluble in methanol||Complies|
|Residue on ignition||≤0.1%||0.03%|
|Conclusion||Up to the Standard USP 32.|
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